A Review on Applications of Bilayer Tablet Technology for Drug Combinations

Bilayer tablets are novel drug delivery systems where combination of two drugs in a single unit having different release profiles can be delivered. improve patient compliance, prolong the drug(s) action and deliver incompatible formulation. have one layer active ingredient for immediate second delayed release, either as dose or an extended fashion. advancing helpful technologies to overcome disadvantages single-layered tablets. However, bilayer tablet technology is resource-intensive. A thorough selection excipients manufacturing conditions each technical stage also required. Patients with high blood pressure often difficulty unable regulate their BP just medication. The majority hypertension patients will need take more antihypertensive medicines order meet treatment goals. Combinations from various categories been found effective than alone treating people whose cannot maintained satisfactorily monotherapy. Combining medications mutually beneficial mechanisms may result much greater lowering efficacy any these components alone. goal this review discuss use administer fixed combinations pressure.
 Keywords: tablet, pressure, drugs, Sustained maintenance dose.